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TNF Receptor-Associated Factor 1 (TRAF1) (Middle Region) Peptide

TRAF1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985436

Aperçu rapide pour TNF Receptor-Associated Factor 1 (TRAF1) (Middle Region) Peptide (ABIN985436)

Antigène

TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-TRAF1 antibody (Catalog #: AVARP09008_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

    Sujet

    This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: EBI6, MGC:10353

    Protein Interaction Partner: BIRC2,BIRC3,MAP3K14,TNFRSF8,TRAF2,BIRC2,BIRC3,CASP10,CASP3,CASP6,CASP8,CD40,CFLAR,EDAR,GFI1B,HIVEP3,MAP3K14,MAP6,NGFRAP1,RIPK1,RIPK2,SPOP,SRC,TANK,TICAM1,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAF3IP2,TRAIP,TRIM37,USP7,BIRC2,BIRC3,CASP10,CASP6,CASP8,CD27,CFLAR,HIVEP3,LTBR,MAP3K14,MAP3K5,NGFR,RIPK1,RIPK2,SPOP,SRC,TANK,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAIP,TRIM37,USP7

    Protein Size: 416

    Poids moléculaire

    46 kDa

    ID gène

    7185

    NCBI Accession

    NM_005658, NP_005649

    UniProt

    Q13077
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